Acanthosis Nigricans: Causes, Symptoms, and Treatment at Al Biraa Clinic
What is Acanthosis Nigricans?
Acanthosis Nigricans is a common skin condition characterized by dark, velvety patches, often appearing on the neck, armpits, groin, and other body folds. Though not harmful, it can be a sign of underlying health issues such as insulin resistance, obesity, or hormonal imbalances. At Al Biraa Clinic, we offer advanced treatment options to help manage and improve the condition effectively.
Acanthosis Nigricans: Commonly Affected Areas and Causes
Acanthosis nigricans is a skin condition characterized by dark, thick, and velvety patches. It typically develops in body areas with folds, friction, or increased insulin sensitivity. Below are the most commonly affected areas and their possible causes.
1. Neck
- The back and sides of the neck are the most frequently affected areas.
- It appears as dark, thickened skin with a velvety texture.
- Often associated with obesity, insulin resistance, or diabetes.
2. Armpits (Axillae)
- Acanthosis nigricans commonly appears in the armpits due to friction and sweating.
- It may also be linked to hormonal imbalances or metabolic conditions.
3. Groin
- The inner thigh and groin area can develop darkened skin.
- This is more common in overweight individuals and those with insulin resistance.
4. Knees and Elbows
- Dark, thickened patches may form on the joints due to frequent bending and friction.
- Common in individuals with obesity or certain endocrine disorders.
5. Knuckles and Fingers
- The skin over knuckles may darken and thicken.
- Often a sign of insulin resistance, polycystic ovary syndrome (PCOS), or prediabetes.
6. Face (Less Common)
- In some cases, dark patches may appear on the forehead or around the lips.
- More prevalent in individuals with genetic predisposition or hormonal conditions.
7. Under the Breasts
- Occurs due to friction, excessive sweating, or weight-related factors.
- Can be exacerbated by fungal infections or poor hygiene.
Causes of Acanthosis Nigricans
Acanthosis nigricans is often a symptom of an underlying health issue, including:
- Insulin resistance – A primary cause, commonly linked to prediabetes and type 2 diabetes.
- Obesity – Excess body weight increases the risk of skin darkening, particularly in skin folds.
- Hormonal disorders – Conditions such as PCOS, Cushing’s syndrome, and hypothyroidism may trigger this condition.
- Certain medications – Some drugs, like steroids and birth control pills, can contribute to the development of acanthosis nigricans.
- Genetics – In some cases, it can be inherited and run in families.
- Cancer-related acanthosis nigricans – Rarely, it may be associated with gastric or other internal malignancies.
When to See a Doctor?
If you notice sudden or widespread skin darkening, especially without weight gain or a family history, consult a healthcare professional. Early diagnosis and treatment of the underlying condition can help manage acanthosis nigricans effectively.
Causes and Risk Factors
Insulin Resistance
Acanthosis Nigricans is strongly associated with insulin resistance, a condition where the body’s cells fail to respond to insulin effectively. This leads to increased insulin levels, stimulating skin cell growth and pigmentation.
Obesity
Excess weight can lead to insulin resistance and increase the risk of Acanthosis Nigricans. Fat accumulation triggers hormonal changes that contribute to skin darkening.
Genetics
Some people inherit a predisposition to Acanthosis Nigricans, making them more likely to develop the condition, even with a healthy lifestyle.
Hormonal Disorders
Conditions such as polycystic ovary syndrome (PCOS), hypothyroidism, and adrenal disorders can contribute to skin thickening and pigmentation changes.
Medications
Certain drugs, including oral contraceptives and corticosteroids, can cause Acanthosis Nigricans as a side effect.
Symptoms and Diagnosis
Common Symptoms
- Dark, velvety skin patches
- Thickened or rough texture
- Itching or irritation (rare)
- Gradual progression over time
How It is Diagnosed
A dermatologist at Al Biraa Clinic can diagnose Acanthosis Nigricans through a physical examination. Blood tests may be required to check for underlying conditions like diabetes or hormonal imbalances.

Acanthosis Nigricans Treatment at Al Biraa Clinic
At Al Biraa Clinic, we offer advanced and customized treatments to improve skin tone and texture, addressing the root cause of Acanthosis Nigricans.
1. Medical Diagnosis & Consultation
Our experts provide a comprehensive skin and health assessment to determine the underlying cause of your condition.
2. Laser Skin Therapy
Laser treatments effectively reduce pigmentation, helping to lighten darkened skin areas and improve texture.
3. Chemical Peels
Medical-grade chemical peels help exfoliate the top layers of dark skin, promoting a smoother and more even skin tone.
4. Microneedling with PRP
Microneedling combined with Platelet-Rich Plasma (PRP) enhances skin regeneration, reducing pigmentation and stimulating collagen production.
5. Microdermabrasion
This non-invasive exfoliation technique removes dead skin cells, improving skin texture and gradually reducing hyperpigmentation.
6. Medical-Grade Skincare Products
We provide dermatologist-approved creams and serums containing active ingredients like retinoids and glycolic acid to help fade dark patches.
7. Lifestyle & Diet Counseling
Since Acanthosis Nigricans is often linked to insulin resistance and obesity, our specialists offer guidance on diet, weight management, and blood sugar control.
At Al Biraa Clinic, we tailor our treatments to your unique skin needs, helping you achieve a brighter and healthier complexion. Book your consultation today!
Preventive Measures
Healthy Diet
A diet low in processed sugars and high in fiber can help prevent insulin spikes and reduce the risk of Acanthosis Nigricans.
Regular Exercise
Physical activity helps regulate insulin levels, reducing the likelihood of developing this condition.
Skin Care Tips
- Use gentle exfoliants to prevent buildup
- Keep skin moisturized
- Protect affected areas from excessive friction
FAQ’S Acanthosis Nigricans
Advanced Laser Treatment for Acanthosis Nigricans at Al Biraa Clinic
Effective Solution for Darkened Skin
Acanthosis Nigricans is a common skin condition that causes dark, thick patches, often appearing on the neck, underarms, and other body folds. At Al Biraa Clinic, we offer advanced laser treatments designed to reduce pigmentation and restore your skin’s natural tone.
How Our Laser Treatment Works
Using state-of-the-art laser technology, our treatment targets excess melanin buildup and stimulates collagen production. This helps to lighten the affected areas, improve skin texture, and promote long-lasting results. The procedure is safe, non-invasive, and suitable for all skin types.
Why Choose Al Biraa Clinic?
- Expert Dermatologists: Our team consists of skilled professionals specializing in laser treatments.
- Personalized Care: Each treatment plan is customized based on individual skin concerns.
- Proven Results: Many satisfied customers have experienced significant improvements with our laser procedures.
Acanthosis Nigricans Treatment Consultation
Acanthosis Nigricans is a manageable condition with proper diagnosis and treatment. At Al Biraa Clinic Dubai, our expert aesthetic dermatologists offer personalized treatment plans to help patients achieve healthier, clearer skin. Book a consultation today to explore the best treatment options for you.